Zink-Versorgung relevant für Zink-abhängige Eiweiße: Biomarker in der Prävention von altersbedingten Erkrankungen
Mikronährstoffversorgung Longevity
Zinkversorgung Prävention
https://www.nature.com/articles/s42255-024-01185-7
Longitudinal serum proteome mapping reveals biomarkers for healthy ageing and related cardiometabolic diseases
"...ten disease-associated ageing proteins can be targeted by zinc and zinc compounds, which could be particularly promising for intervention as zinc is essential for immune responses and protein synthesis and is frequently deficient in the elderly population...".
Tang, J., Yue, L., Xu, Y. et al. Longitudinal serum proteome mapping reveals biomarkers for healthy ageing and related cardiometabolic diseases. Nat Metab 7, 166–181 (2025). https://doi.org/10.1038/s42255-024-01185-7
Heilpilz-Extrakt Cordyceps Militaris verbessert die Wirkung von Immuntherapie bei Krebserkrankungen
Phytotherapie in der Onkologie
Pflanzenheilkunde in der Onkologie
https://www.nature.com/articles/s41598-024-72833-x
Enhancing cancer immunotherapy using cordycepin and Cordyceps militaris extract to sensitize cancer cells and modulate immune responses
"...Integrating immunotherapy with natural compounds holds promise in enhancing the immune system’s ability to eliminate cancer cells. Cordyceps militaris, a traditional Chinese medicine, emerges as a promising candidate in this regard.... Co-culturing cancer cells with effector immune cells during cordycepin or Cm-EE incubation resulted in elevated cancer cell death..."
Thepmalee, C., Jenkham, P., Ramwarungkura, B. et al. Enhancing cancer immunotherapy using cordycepin and Cordyceps militaris extract to sensitize cancer cells and modulate immune responses. Sci Rep 14, 21907 (2024). https://doi.org/10.1038/s41598-024-72833-x
Ketogene Ernährung könnte bei Östrogen-Rezeptor-positiven BrustkrebspatientInnen unter Fulvestrant das Überleben verbessern
Metabolische Therapie in der Onkologie
Ernährung in der Onkologie
https://www.nature.com/articles/s41523-024-00715-6
Co-targeting of metabolism using dietary and pharmacologic approaches reduces breast cancer metastatic burden
"We found that Fulv treatment downregulates the ketogenesis pathway enzyme OXCT1, leading to β-hydroxybutyrate accumulation and decreased tumor cell viability...These findings establish the molecular basis and clinical potential of a ketogenic diet to enhance Fulv efficacy in patients with ER+ liver metastatic breast cancer, potentially improving survival outcomes and quality of life in this population."
Zuo, Q., Yoo, J.Y., Nelson, E.R. et al. Co-targeting of metabolism using dietary and pharmacologic approaches reduces breast cancer metastatic burden. npj Breast Cancer 11, 3 (2025). https://doi.org/10.1038/s41523-024-00715-6